CRISPR-Cas9 Allows Scientists to Edit DNA With Unprecedented Precision
Biology

CRISPR-Cas9 Allows Scientists to Edit DNA With Unprecedented Precision

CRISPR-Cas9 is a molecular tool derived from a bacterial immune system that allows scientists to cut, edit, or silence specific genes with extraordinary precision. First harnessed for genome editing in 2012, it has since revolutionised biology and medicine. By 2023, the first CRISPR-based therapy (for sickle cell disease) was approved by the FDA. The tool works like molecular scissors guided by a RNA 'map' to the exact gene sequence needing editing.

Source

Doudna, J.A. & Charpentier, E. (2012). A programmable dual-RNA-guided DNA endonuclease. Science, 337(6096).

Details

Published
April 21, 2026
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BiologyGeneticsBiotechnologyMedicine

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